Acteoside, a component of Stachis Sieboldii MI’Q, inhibits the induction of ICAM-1 by TNF-α in endothelial cells and mesangial cells

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15 صفحه اول

Acteoside, a component of Stachys sieboldii MIQ, may be a promising antinephritic agent (2): Effect of acteoside on leukocyte accumulation in the glomeruli of nephritic rats.

We investigated the effect of acteoside in comparison with that of cyclosporin A on leukocyte accumulation in the glomeruli of rats with crescentic-type anti-glomerular basement membrane (GBM) nephritis. Acteoside given p.o. at a dose of 30 mg/kg once a day for 15 consecutive days after treatment with anti-GBM serum markedly suppressed the urinary protein as well as glomerular histological chan...

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ژورنال

عنوان ژورنال: Japanese Journal of Pharmacology

سال: 1995

ISSN: 0021-5198

DOI: 10.1016/s0021-5198(19)47095-9